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3500xL Genetic Analyzer

 

Catalog number:  4405633

 

Description:

The 3500xL Genetic Analyzer is a 24-capillary sequencing platform that can be used for a wide variety of applications, including de novo sequencing and resequencing (mutational profiling), as well as microsatellite analysis, MLPA™, LOH, MLST, and SNP validation or screening. The majority of applications can be run on a single polymer and capillary array.

This package includes a 24-capillary instrument, 3500 Series Data Collection Software, and a Dell™ Workstation and monitor. The 3500 Series Data Collection Software supports sequencing and fragment analysis, and integrates seamlessly with several downstream software packages (not included) for secondary analysis of genetic data.


Features of the 3500xL Genetic Analyzer include:

  • Single-line, 505 nm, solid-state. long-life laser that uses a standard power supply and requires no heat-removal ducting
  • Powerful, integrated data collection and primary analysis software provides real-time assessment of data quality
  • Radio frequency identification (RFID) technology tracks key consumables data and records administrative information
  • Advanced multiplexing capabilities for DNA fragment analysis with up to six unique dyes
  • Unrivaled application flexibility—one array and one polymer are used for most applications
  • Simple setup, operation, and maintenance

Offering accurate reliable data quality
The 3500 Series genetic analyzers are designed to significantly improve signal uniformity from instrument-to-instrument, run-to-run, and capillary-to-capillary. With a combination of intelligent hardware, powerful algorithm and reagent combinations, these methods enable major reduction in the range of signal peak heights obtained across multiple 3500 series instruments (see figure).

Improved sizing precision
The thermal sub-system design gives enhanced performance in demanding fragment applications, enabling improved sizing precision versus previous generations of capillary electrophoresis platforms.

Ready-to-use consumables with RFID tags
The 3500 Series offers ready-to-use consumables with pre-packaged polymer pouches, cathode and anode buffer containers, and easy-to-install capillary arrays. Each of these consumables is integrated with RFID tags that enable viewing, tracking, and reporting of critical information about reagents and consumables including usage, lot number, part number, expiry date, and on-instrument lifetime within the 3500 Series Data Collection Software.

Easy-to-use data collection software
The 3500 Series Data Collection Software breaks ground in user-friendly navigation with an intuitive dashboard design, highly visible buttons for common operations, easy-to-read graphical displays to monitor the state of consumables, and a handy maintenance scheduling calendar functionality. Functionality includes simplified plate set-up and built-in primary analysis with quality control, so you can make decisions about the quality of data as it is produced on the instrument without the need to transfer output files into secondary analysis software packages.

Specification:
Analysis Software: GeneMapper® Software, Sequencing Analysis Software, Variant Reporter® Software
Capillary Length: 36 cm50 cm
Compatible Polymers: POP-4™, POP-6™, POP-7™
Current Limit: 15 amps
External Computer: Hard Drive: 2x 500GB SATA 3.0 Gb/s and 8 MB Data Burst Cache, Memory: 16 GB (2x 8GB) 1600 MHz DDR3 Non-ECC. 4th Gen Intel Core I7 Processor- 3.1 GHz Turbo Processor, Operating System: Windows 7 SP1
For Use With (Equipment): 3500xL Genetic Analyzer
Green Features: Energy efficient, Fewer resources used and less waste
Operating System: Win 7 (Service Pack 1)
Plan Duration: 1 Year Limited Warranty on Parts and Labor, Service Installation and Application Training Included
Product Size: 1 system
Shipping Condition: Room Temperature
Throughput: Up to 1104 samples per day (using run module ShortReadSeqPOP7)
Weight: 82 kg (approximately)

         

 

 

                

 

3500 Series Genetic Analyzers - Overview

It's accurate
Based on one of the most widely used, widely trusted sequencing methodologies available—Sanger sequencing—the 3500 Series Genetic Analyzer is designed to deliver the accuracy you demand.

It works the way you do
Designed with you in mind, the 3500 Series Genetic Analyzer gives you automated operation, easy-to-install consumables, electronic tracking of instrument performance and maintenance tasks, and integrated analysis software—so you can focus on the outcome.

It's flexible
The 3500 platform can run a wide variety of applications, including de novosequencing and resequencing (mutational profiling), microsatellite analysis, MLPA, AFLP, LOH, MLST, and SNP validation or screening.

It's backed by award-winning support
Keeping your lab operational is critical. Our technical and field service support staffs respond quickly to your calls, so that you can continue to respond to those who depend on you for results.

             

 

                      

 

Applied Biosystems™ - 3500 და 3500xL - System components

Feature Benefit
RFID Instrument automatically checks for the use of correct product and expiration dates
SAE Security, audit and electronic signature capability to help compliance with governing regulations
8-capillary or 24-capillary models Select the appropriate instrument to meet your laboratory throughput needs
Flexibility Allows you to adhere to your lab's development requirements—sequencing or fragment analysis applications

The Applied Biosystems™ 3500 and 3500xL Genetic Analyzers are supplied as follows:

  • Capillary electrophoresis instrument
  • 8-capillary (3500 System) or 24-capillary (3500xL System) array and polymer
  • DNA sequencing and/or fragment analysis reagents and consumables for system qualification
  • Dell™ computer workstation with flat-screen monitor
  • Integrated software for instrument control, data collection, quality control, and auto-analysis of sample files for basecalling and fragment sizing